Toulouse, an important county in southern France, was centered on the town of Toulouse. Controlling the trade routes into Spain and Italy, the counts of Toulouse dominated much of Languedoc between the Rivers Rhône and Garonne in the eleventh and twelfth centuries. Implicated in the Cathar heresy, a movement that was destroyed by the Albigensian crusaders from northern France in the early thirteenth century, the counts of Toulouse lost influence and the county came eventually into the possession of Alphonse of Poitiers, the brother of Louis IX of France. From the 1270s, the region was under royal control, although the town of Toulouse enjoyed considerable autonomy. The region was particularly hard hit by the English Chevauche ´e of 1355, during which Edward, the Black Prince, destroyed many towns and villages in the county, and by the activities of routiers in the 1360s. In the 1420s, Toulouse was a center of dauphinist support.